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Publications by Ernest Hamel

Optimization of N-Aryl-6-Methoxy-1,2,3,4-Tetrahydroquinolines as Tubulin Polymerization Inhibitors

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2015English

Synthesis and Biological Evaluation of N-Alkyl-N-(4-Methoxyphenyl)pyridin-2-Amines as a New Class of Tubulin Polymerization Inhibitors

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2013English

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3′,4′,5′-Trimethoxyanilino)-3,6-Disubstituted-4,5,6,7-Tetrahydrothieno[2,3-C]pyridine Scaffold

Molecules
Organic ChemistryMolecular MedicineAnalytical ChemistryTheoretical ChemistryPharmaceutical ScienceMedicineDrug DiscoveryChemistryPhysical
2020English

Antitumor Agents 273. Design and Synthesis of N-Alkyl-Thiocolchicinoids as Potential Antitumor Agents

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

Identification of Diaryl 5-Amino-1,2,4-Oxadiazoles as Tubulin Inhibitors: The Special Case of 3-(2-Fluorophenyl)-5-(4-Methoxyphenyl)amino-1,2,4-Oxadiazole

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2013English

Synthesis and Biological Evaluation of Biaryl Analogs of Antitubulin Compounds

Quimica Nova
Chemistry
2012English

(−)-Doliculide, a New Macrocyclic Depsipeptide Enhancer of Actin Assembly

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2002English

Direct Photoaffinity Labeling of Cysteine-295 of Α-Tubulin by Guanosine 5′-Triphosphate Bound in the Nonexchangeable Site

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
1998English

2-Arylamino-4-Amino-5-Aroylthiazoles. “One-Pot” Synthesis and Biological Evaluation of a New Class of Inhibitors of Tubulin Polymerization

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2009English

Design and Synthesis of 2-(3-Benzo[b]thienyl)-6,7-Methylenedioxyquinolin-4-One Analogues as Potent Antitumor Agents That Inhibit Tubulin Assembly

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2009English

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