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Publications by Ernesto Freire

Crystal Structures of Trimeric HIV Envelope With Entry Inhibitors BMS-378806 and BMS-626529

Nature Chemical Biology
Cell BiologyMolecular Biology
2017English

SOSIP Changes Affect Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Conformation and CD4 Engagement

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
2018English

Chemical Denaturation as a Tool in the Formulation Optimization of Biologics

Drug Discovery Today
Drug DiscoveryPharmacology
2013English

Non-Natural Peptide Triazole Antagonists of HIV-1 Envelope Gp120

ChemMedChem
Organic ChemistryMolecular MedicinePharmacologyBiochemistryToxicologyDrug DiscoveryPharmaceutics
2012English

Design, Synthesis and Biological Evaluation of Small Molecule Inhibitors of CD4-gp120 Binding Based on Virtual Screening

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2011English

Isothermal Chemical Denaturation to Determine Binding Affinity of Small Molecules to G-Protein Coupled Receptors

Analytical Biochemistry
BiochemistryCell BiologyMolecular BiologyBiophysics
2015English

Ligand Binding Analysis and Screening by Chemical Denaturation Shift

Analytical Biochemistry
BiochemistryCell BiologyMolecular BiologyBiophysics
2013English

How Much Binding Affinity Can Be Gained by Filling a Cavity?

Chemical Biology and Drug Design
BiochemistryOrganic ChemistryDrug DiscoveryMolecular MedicinePharmacology
2010English

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