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Publications by Frances H. Arnold

An Enzymatic Platform for the Asymmetric Amination of Primary, Secondary and Tertiary C(sp3)–H Bonds

Nature Chemistry

Chemical Engineering

English

Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble

Journal of the American Chemical Society

Surface Chemistry

English

Tailoring Tryptophan Synthase TrpB for Selective Quaternary Carbon Bond Formation

Journal of the American Chemical Society

Surface Chemistry

English

Nitrene Transfer Catalyzed by a Non-Heme Iron Enzyme and Enhanced by Non-Native Small-Molecule Ligands

Journal of the American Chemical Society

Surface Chemistry

English

Identification of Mechanism-Based Inactivation in P450-Catalyzed Cyclopropanation Facilitates Engineering of Improved Enzymes

Journal of the American Chemical Society

Surface Chemistry

English

A Panel of TrpB Biocatalysts Derived From Tryptophan Synthase Through the Transfer of Mutations That Mimic Allosteric Activation

Angewandte Chemie - International Edition

English

Directed Evolution of the Tryptophan Synthase Β-Subunit for Stand-Alone Function Recapitulates Allosteric Activation

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English

Expanding the Enzyme Universe: Accessing Non-Natural Reactions by Mechanism-Guided Directed Evolution

Angewandte Chemie - International Edition

English

Innovation by Evolution: Bringing New Chemistry to Life (Nobel Lecture)

Angewandte Chemie - International Edition

English

Machine Learning-Assisted Directed Protein Evolution With Combinatorial Libraries

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English