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Publications by Frank Sicheri

An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme

Molecular Biology

English

Metformin Reduces Liver Glucose Production by Inhibition of Fructose-1-6-Bisphosphatase

Nature Medicine

Molecular Biology

English

Pharmacological Targeting of MYC-regulated IRE1/XBP1 Pathway Suppresses MYC-driven Breast Cancer

Journal of Clinical Investigation

English

Putting the Brakes on the Unfolded Protein Response: Figure 1.

Journal of Cell Biology

English

An Allosteric Conduit Facilitates Dynamic Multisite Substrate Recognition by the SCFCdc4 Ubiquitin Ligase

Nature Communications

Molecular Biology

English

Mechanism of Catalysis, E2 Recognition, and Autoinhibition for the IpaH Family of Bacterial E3 Ubiquitin Ligases

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English

Inhibition of SCF Ubiquitin Ligases by Engineered Ubiquitin Variants That Target the Cul1 Binding Site on the Skp1–F-Box Interface

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English

Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15

Structural Biology

Molecular Biology

English

Structure/Function Implications in a Dynamic Complex of the Intrinsically Disordered Sic1 With the Cdc4 Subunit of an SCF Ubiquitin Ligase

Structural Biology

Molecular Biology

English

Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment

Structural Biology

Molecular Biology

English