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Publications by James Shorter

Potentiated Hsp104 Variants Antagonize Diverse Proteotoxic Misfolding Events

Cell
BiochemistryGeneticsMolecular Biology
2014English

The Hsp104 N-Terminal Domain Enables Disaggregase Plasticity and Potentiation

Molecular Cell
Cell BiologyMolecular Biology
2015English

Cytoplasmic TDP-43 De-Mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death

Neuron
Neuroscience
2019English

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

Neuron
Neuroscience
2019English

Spiral Architecture of the Hsp104 Disaggregase Reveals the Basis for Polypeptide Translocation

Nature Structural and Molecular Biology
Structural BiologyMolecular Biology
2016English

Enhancement of Ebola Virus Infection by Seminal Amyloid Fibrils

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2018English

Hydrogen Exchange Reveals Hsp104 Architecture, Structural Dynamics, and Energetics in Physiological Solution

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2019English

3′ UTRs in the Eye of the TIGER

Developmental Cell
BiochemistryDevelopmental BiologyGeneticsCell BiologyMolecular Biology
2018English

Small Heat Shock Proteins Potentiate Amyloid Dissolution by Protein Disaggregases From Yeast and Humans

PLoS Biology
ImmunologyMolecular BiologyGeneticsBiochemistryMicrobiology Biological SciencesAgriculturalNeuroscience
2012English

Specific Aromatic Foldamers Potently Inhibit Spontaneous and Seeded Aβ42 and Aβ43 Fibril Assembly

Biochemical Journal
BiochemistryCell BiologyMolecular Biology
2014English

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