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Publications by John Lunec
A DHODH Inhibitor Increases P53 Synthesis and Enhances Tumor Cell Killing by P53 Degradation Blockage
Nature Communications
Astronomy
Genetics
Molecular Biology
Biochemistry
Chemistry
Physics
ATM Dependent DUSP6 Modulation of P53 Involved in Synergistic Targeting of MAPK and P53 Pathways With Trametinib and MDM2 Inhibitors in Cutaneous Melanoma
Cancers
Cancer Research
Oncology
Pre-Clinical Efficacy and Synergistic Potential of the MDM2-p53 Antagonists, Nutlin-3 and RG7388, as Single Agents and in Combined Treatment With Cisplatin in Ovarian Cancer
Oncotarget
Oncology
Nutlin-3 Inhibits Androgen Receptor-Driven C-Flip Expression, Resulting in Apoptosis of Prostate Cancer Cells
Oncotarget
Oncology
Pattern of Nucleotide Variants of TP53 and Their Correlation With the Expression of P53 and Its Downstream Proteins in a Sri Lankan Cohort of Breast and Colorectal Cancer Patients
BMC Cancer
Cancer Research
Oncology
Genetics
TP53 Mutant Cell Lines Selected for Resistance to MDM2 Inhibitors Retain Growth Inhibition by MAPK Pathway Inhibitors but a Reduced Apoptotic Response
Cancer Cell International
Cancer Research
Oncology
Genetics
Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach
Chemical Biology and Drug Design
Biochemistry
Organic Chemistry
Drug Discovery
Molecular Medicine
Pharmacology