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Publications by Jolanta Grembecka

Combined MAPK Pathway and HDAC Inhibition Breaks Melanoma

Cancer Discovery
Oncology
2019English

Pharmacologic Inhibition of the Menin-MLL Interaction Leads to Transcriptional Repression of PEG10 and Blocks Hepatocellular Carcinoma

Molecular Cancer Therapeutics
Cancer ResearchOncology
2017English

Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein–Protein Interaction Between Menin and Mixed Lineage Leukemia (MLL)

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2016English

Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase

Biochemistry
Biochemistry
2015English

Cytokine Induced Phenotypic and Epigenetic Signatures Are Key to Establishing Specific Macrophage Phenotypes

PLoS ONE
Multidisciplinary
2013English

Challenges and Opportunities in Targeting the Menin–MLL Interaction

Future Medicinal Chemistry
Drug DiscoveryMolecular MedicinePharmacology
2014English

Structure of the MLL CXXC Domain–DNA Complex and Its Functional Role in MLL-AF9 Leukemia

Nature Structural and Molecular Biology
Structural BiologyMolecular Biology
2009English

Structural Basis for the Inhibition of the Essential Plasmodium Falciparum M1 Neutral Aminopeptidase

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2009English

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