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Publications by Jolanta Grembecka
Combined MAPK Pathway and HDAC Inhibition Breaks Melanoma
Cancer Discovery
Oncology
Pharmacologic Inhibition of the Menin-MLL Interaction Leads to Transcriptional Repression of PEG10 and Blocks Hepatocellular Carcinoma
Molecular Cancer Therapeutics
Cancer Research
Oncology
Property Focused Structure-Based Optimization of Small Molecule Inhibitors of the Protein–Protein Interaction Between Menin and Mixed Lineage Leukemia (MLL)
Journal of Medicinal Chemistry
Drug Discovery
Molecular Medicine
Two Loops Undergoing Concerted Dynamics Regulate the Activity of the ASH1L Histone Methyltransferase
Biochemistry
Biochemistry
Cytokine Induced Phenotypic and Epigenetic Signatures Are Key to Establishing Specific Macrophage Phenotypes
PLoS ONE
Multidisciplinary
Challenges and Opportunities in Targeting the Menin–MLL Interaction
Future Medicinal Chemistry
Drug Discovery
Molecular Medicine
Pharmacology
Structure of the MLL CXXC Domain–DNA Complex and Its Functional Role in MLL-AF9 Leukemia
Nature Structural and Molecular Biology
Structural Biology
Molecular Biology
Structural Basis for the Inhibition of the Essential Plasmodium Falciparum M1 Neutral Aminopeptidase
Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary