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Publications by Jonathan M. Ostrem
K-Ras(G12C) Inhibitors Allosterically Control GTP Affinity and Effector Interactions
Nature
Multidisciplinary
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Direct Ras G12C Inhibitors: Crossing the Rubicon
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Increased Frequency of the K-Ras G12C Mutation in MYH Polyposis Colorectal Adenomas
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GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site
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Differential Interaction of the Ras Family GTP-binding Proteins H-Ras, Rap1A, and R-Ras With the Putative Effector Molecules Raf Kinase and Ral-Guanine Nucleotide Exchange Factor
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Identification of the Guanine Nucleotide Dissociation Stimulator for Ral as a Putative Effector Molecule of R-Ras, H-Ras, K-Ras, and Rap
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The Structural Basis for the Transition From Ras-GTP to Ras-GDP
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Genetic Definition of Ras Effector Elements.
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1H, 15N Backbone Assignment and Comparative Analysis of the Wild Type and G12C, G12D, G12V Mutants of K-Ras Bound to GDP at Physiological pH
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Ras Functional Proximity Proteomics Establishes mTORC2 as New Direct Ras Effector
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