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Publications by Julian Downward

Coordinate Direct Input of Both KRAS and IGF1 Receptor to Activation of PI3 Kinase in KRAS -Mutant Lung Cancer

Cancer Discovery

English

Determination of Synthetic Lethal Interactions in KRAS Oncogene-Dependent Cancer Cells Reveals Novel Therapeutic Targeting Strategies

Molecular Biology

English

Paracrine Signalling During ZEB1-mediated Epithelial–mesenchymal Transition Augments Local Myofibroblast Differentiation in Lung Fibrosis

Cell Death and Differentiation

Molecular Biology

English

AKT Signalling Selectively Regulates PINK1 Mitophagy in SHSY5Y Cells and Human iPSC-derived Neurons

Scientific Reports

Multidisciplinary

English

Inherited Duplications of PPP2R3B Promote Naevi and Melanoma via a Novel C21orf91-Driven Proliferative Phenotype

English

Intramolecular and Intermolecular Interactions of Protein Kinase B Define Its Activation in Vivo

Molecular Biology

Biological Sciences

English

Mechanism of Epidermal Growth Factor Regulation of Vav2, a Guanine Nucleotide Exchange Factor for Rac

Journal of Biological Chemistry

Molecular Biology

English

Full Oncogenic Activities of V-SRC Are Mediated by Multiple Signaling Pathways

Journal of Biological Chemistry

Molecular Biology

English

Binding Specificity and Regulation of the Serine Protease and PDZ Domains of HtrA2/Omi

Journal of Biological Chemistry

Molecular Biology

English

CUTL1 Is Phosphorylated by Protein Kinase A, Modulating Its Effects on Cell Proliferation and Motility

Journal of Biological Chemistry

Molecular Biology

English