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Publications by K. Dane Wittrup

Stability and CDR Composition Biases Enrich Binder Functionality Landscapes

Journal of Molecular Biology
Structural BiologyMolecular BiologyBiophysics
2010English

Differential Requirement for CD70 and CD80/CD86 in Dendritic Cell-Mediated Activation of Tumor-Tolerized CD8 T Cells

Journal of Immunology
AllergyImmunology
2012English

Order of Administration of Combination Cytokine Therapies Can Decouple Toxicity From Efficacy in Syngeneic Mouse Tumor Models

OncoImmunology
OncologyAllergyImmunology
2019English

Strong Enrichment of Aromatic Residues in Binding Sites From a Charge-Neutralized Hyperthermostable Sso7d Scaffold Library

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2016English

Bispecific Designed Ankyrin Repeat Proteins (DARPins) Targeting Epidermal Growth Factor Receptor Inhibit A431 Cell Proliferation and Receptor Recycling

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2011English

Purification of Common Light Chain IgG-like Bispecific Antibodies Using Highly Linear pH Gradients

mAbs
AllergyImmunology
2016English

Picomolar Affinity Fibronectin Domains Engineered Utilizing Loop Length Diversity, Recursive Mutagenesis, and Loop Shuffling

Journal of Molecular Biology
Structural BiologyMolecular BiologyBiophysics
2008English

Degradation of Mutated Bovine Pancreatic Trypsin Inhibitor in the Yeast Vacuole Suggests Post-Endoplasmic Reticulum Protein Quality Control

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2004English

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