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Publications by Ke-He Ruan

Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy

Cancer Research
Cancer ResearchOncology
2018English

Inducible COX-2 Dominates Over COX-1 in Prostacyclin Biosynthesis: Mechanisms of COX-2 Inhibitor Risk to Heart Disease

Life Sciences
GeneticsMolecular BiologyPharmacologyBiochemistryMedicineToxicologyPharmaceutics
2011English

An Agonist Sensitive, Quick and Simple Cell-Based Signaling Assay for Determination of Ligands Mimicking Prostaglandin E2 or E1 Activity Through Subtype EP1 Receptor: Suitable for High Throughput Screening

BMC Complementary and Alternative Medicine
MedicineAlternative MedicineComplementary
2011English

Recent Advances and Near Future of Insulin Production and Therapy

Future Medicinal Chemistry
Drug DiscoveryMolecular MedicinePharmacology
2019English

Prostacyclin Synthase Active Sites

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
1997English

Involvement of Non-Conserved Residues Important for PGE2binding to the Constrained EP3 eLP2using NMR and Site-Directed Mutagenesis

FEBS Letters
GeneticsCell BiologyMolecular BiologyBiochemistryStructural BiologyBiophysics
2008English

Large-Scale Expression, Purification, and Characterization of an Engineered Prostacyclin-Synthesizing Enzyme With Therapeutic Potential

Archives of Biochemistry and Biophysics
BiochemistryMolecular BiologyBiophysics
2008English

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