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Publications by Kenneth A. Jacobson

Structure of the Human P2Y12 Receptor in Complex With an Antithrombotic Drug

Nature
Multidisciplinary
2014English

Physiology and Effects of Nucleosides in Mice Lacking All Four Adenosine Receptors

PLoS Biology
ImmunologyMolecular BiologyGeneticsBiochemistryMicrobiology Biological SciencesAgriculturalNeuroscience
2019English

GPCR Ligand–dendrimer (GLiDe) Conjugates: Future Smart Drugs?

Trends in Pharmacological Sciences
ToxicologyPharmacology
2010English

On the Selectivity of the Gαq Inhibitor UBO-QIC: A Comparison With the Gαi Inhibitor Pertussis Toxin

Biochemical Pharmacology
BiochemistryPharmacology
2016English

Metabolic Mapping of A3 Adenosine Receptor Agonist MRS5980

Biochemical Pharmacology
BiochemistryPharmacology
2015English

Species Differences and Mechanism of Action of A3 Adenosine Receptor Allosteric Modulators

Purinergic Signalling
Molecular NeuroscienceCell BiologyMolecular BiologyCellular
2017English

The Therapeutic Effect of 2-Cyclohexylthio-Amp in Heart Failure

Journal of Cardiovascular Pharmacology
Cardiovascular MedicinePharmacologyCardiology
2013English

2-Dialkynyl Derivatives of (N)-Methanocarba Nucleosides: ‘Clickable’ A3 Adenosine Receptor-Selective Agonists

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

Synthesis and Pharmacological Characterization of a New Series of 5,7-Disubstituted-[1,2,4]triazolo[1,5-A][1,3,5]triazine Derivatives as Adenosine Receptor Antagonists: A Preliminary Inspection of Ligand–receptor Recognition Process

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

Extended N6 Substitution of Rigid C2-Arylethynyl Nucleosides for Exploring the Role of Extracellular Loops in Ligand Recognition at the A3 Adenosine Receptor

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2014English

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