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Publications by Lina M. Obeid

Structure of Human nSMase2 Reveals an Interdomain Allosteric Activation Mechanism for Ceramide Generation

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English

Still Benched on Its Way to the Bedside: Sphingosine Kinase 1 as an Emerging Target in Cancer Chemotherapy

Critical Reviews in Biochemistry and Molecular Biology

Molecular Biology

English

Tumor Suppressor P53 Links Ceramide Metabolism to DNA Damage Response Through Alkaline Ceramidase 2

Cell Death and Differentiation

Molecular Biology

English

Sphingosine 1-Phosphate and Sphingosine Kinase Are Involved in a Novel Signaling Pathway Leading to Acrosomal Exocytosis

Journal of Biological Chemistry

Molecular Biology

English

Oncogenic K-Ras Regulates Bioactive Sphingolipids in a Sphingosine Kinase 1-Dependent Manner

Journal of Biological Chemistry

Molecular Biology

English

Inhibiting Glucosylceramide Synthase Exacerbates Cisplatin-Induced Acute Kidney Injury

Journal of Lipid Research

English

Advances in Determining Signaling Mechanisms of Ceramide and Role in Disease

Journal of Lipid Research

English

Selective Knockdown of Ceramide Synthases Reveals Complex Interregulation of Sphingolipid Metabolism

Journal of Lipid Research

English

Inhibition of Sphingosine Kinase-2 in a Murine Model of Lupus Nephritis

Multidisciplinary

English

Impact of Sphingosine Kinase 2 Deficiency on the Development of TNF-alpha-induced Inflammatory Arthritis

Rheumatology International

English