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Publications by Linda Millen
Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling Between the Binding Site and the NBD1:CL4 Interface
Molecular Pharmacology
Molecular Medicine
Pharmacology
Related publications
Optimization of the NBD1 Site Improves the Function of G551d-CFTR Channels
Biophysical Journal
Biophysics
Integrating the Signals: Implications of CFTR NBD1 Allostery to Cystic Fibrosis
Biophysical Journal
Biophysics
The CFTR Corrector, VX-809 (Lumacaftor), Rescues ABCA4 Trafficking Mutants: A Potential Treatment for Stargardt Disease
Cellular Physiology and Biochemistry
Physiology
Direct Measurements of VEGF:VEGFR2 Binding Affinities Reveal the Coupling Between Ligand Binding and Receptor Dimerization
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
CFTR Regulatory Region Interacts With NBD1 Predominantly via Multiple Transient Helices
Nature Structural and Molecular Biology
Structural Biology
Molecular Biology
An Allosteric Ligand-Binding Site in the Extracellular Cap of K2P Channels
Nature Communications
Astronomy
Genetics
Molecular Biology
Biochemistry
Chemistry
Physics
Homology Modeling of the Transmembrane Domain of the Human Calcium Sensing Receptor and Localization of an Allosteric Binding Site
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
After the Structure Comes the Dynamics: Molecular Modeling of Glutamate Receptors Reveals Long-Range Allosteric Coupling Between Ligand Binding Site and Channel Gate
Biophysical Journal
Biophysics
Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP
Structure
Structural Biology
Molecular Biology