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Publications by ML Smidt

In vitroSequential Selection and Characterization of Human Immunodeficiency Virus Type 1 Variants With Reduced Sensitivity to Hydroxyethylurea Protease Inhibitors

Antiviral Chemistry and Chemotherapy
MedicineVirologyDrug DiscoveryPharmacology
1997English

Related publications

In Vitro Selection and Characterization of Human Immunodeficiency Virus Type 1 (HIV-1) Isolates With Reduced Sensitivity to Hydroxyethylamino Sulfonamide Inhibitors of HIV-1 Aspartyl Protease.

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
1995English

Novel Human Immunodeficiency Virus Type 1 Protease Mutations Potentially Involved in Resistance to Protease Inhibitors

Antimicrobial Agents and Chemotherapy
Infectious DiseasesPharmacology
2005English

Cross-Resistance Analysis of Human Immunodeficiency Virus Type 1 Variants Individually Selected for Resistance to Five Different Protease Inhibitors

Antimicrobial Agents and Chemotherapy
Infectious DiseasesPharmacology
1995English

Constrained Evolution of Human Immunodeficiency Virus Type 1 Protease During Sequential Therapy With Two Distinct Protease Inhibitors

Journal of Virology
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1999English

Amino Acid Insertions Near Gag Cleavage Sites Restore the Otherwise Compromised Replication of Human Immunodeficiency Virus Type 1 Variants Resistant to Protease Inhibitors

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
2004English

Crystal Structure of Human Immunodeficiency Virus (HIV) Type 2 Protease in Complex With a Reduced Amide Inhibitor and Comparison With HIV-1 Protease Structures.

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
1993English

Loss of Viral Fitness Associated With Multiple Gag and Gag-Pol Processing Defects in Human Immunodeficiency Virus Type 1 Variants Selected for Resistance to Protease Inhibitors in Vivo

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
1998English

Intracellular Expression of Human Immunodeficiency Virus Type 1 (HIV-1) Protease Variants Inhibits Replication of Wild-Type and Protease Inhibitor-Resistant HIV-1 Strains in Human T-Cell Lines.

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
1996English

Engineering Human Immunodeficiency Virus 1 Protease Heterodimers as Macromolecular Inhibitors of Viral Maturation.

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
1996English

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