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Publications by Madhavi Challa-Malladi

The Apaf-1•procaspase-9 Apoptosome Complex Functions as a Proteolytic-Based Molecular Timer

Molecular Biology

English

Related publications

cIAP1 Cooperatively Inhibits Procaspase-3 Activation by the Caspase-9 Apoptosome

Journal of Biological Chemistry

Molecular Biology

English

Changes in Apaf-1 Conformation That Drive Apoptosome Assembly

English

BCL-Xl Interacts With Apaf-1 and Inhibits Apaf-1-Dependent Caspase-9 Activation

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English

Molecular Dynamics Simulation of the Conformational Changes in the Procaspase 9 Activation

Biophysical Journal

English

Regulation of Caspase-9 Activity by Differential Binding to the Apoptosome Complex

Frontiers in Bioscience - Landmark

Molecular Biology

English

Modeling of Interaction Between Cytochrome C and the WD Domains of Apaf-1: Bifurcated Salt Bridges Underlying Apoptosome Assembly

Molecular Biology

Applied Mathematics

Biological Sciences

English

Intracellular K+ Inhibits Apoptosis by Suppressing the Apaf-1 Apoptosome Formation and Subsequent Downstream Pathways but Not Cytochrome C Release

Cell Death and Differentiation

Molecular Biology

English

The Proteolytic Fragments of the Alzheimer’s Disease-Associated Presenilin-1 Form Heterodimers and Occur as a 100–150-kDa Molecular Mass Complex

Journal of Biological Chemistry

Molecular Biology

English

An Epistatic Effect of Apaf-1 and Caspase-9 on Chlamydial Infection

Apoptosis : an international journal on programmed cell death

Clinical Biochemistry

Cancer Research

Pharmaceutical Science

English