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Publications by Matthew G. Vander Heiden

Metabolic Targets for Cancer Therapy

Nature Reviews Drug Discovery
MedicineDrug DiscoveryPharmacology
2013English

Reactive Metabolite Production Is a Targetable Liability of Glycolytic Metabolism in Lung Cancer

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2019English

Targeting Metabolism for Cancer Therapy

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2017English

A Fundamental Trade-Off in Covalent Switching and Its Circumvention by Enzyme Bifunctionality in Glucose Homeostasis

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2014English

Cooperative Nutrient Accumulation Sustains Growth of Mammalian Cells

Scientific Reports
Multidisciplinary
2015English

Cancer-Associated IDH1 Mutations Produce 2-Hydroxyglutarate

Nature
Multidisciplinary
2009English

BCL-xLComplementsSaccharomyces cerevisiaeGenes That Facilitate the Switch From Glycolytic to Oxidative Metabolism

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2002English

Role of Oxidative Phosphorylation in Bax Toxicity

Molecular and Cellular Biology
Cell BiologyMolecular Biology
2000English

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