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Publications by Mellissa Clark

Biased Ligand Quantification in Drug Discovery: From Theory to High Throughput Screening to Identify New Biased Μ Opioid Receptor Agonists

British Journal of Pharmacology
Pharmacology
2016English

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Biased Receptor Signaling in Drug Discovery

Pharmacological Reviews
Molecular MedicinePharmacology
2019English

Discovery of G Protein-Biased EP2 Receptor Agonists

English

New Gi-Protein Biased Μ-Opioid Receptor Ligands Act as Partial Agonists on Ion Channel Effectors of Gβγ Signaling

Biophysical Journal
Biophysics
2019English

Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2016English

Characterization of Methadone as a Β-Arrestin-Biased Μ-Opioid Receptor Agonist

Molecular Pain
Molecular MedicineAnesthesiologyPain MedicineCellularMolecular Neuroscience
2016English

A Tetrapeptide Class of Biased Analgesics From an Australian Fungus Targets the Μ-Opioid Receptor

Proceedings of the National Academy of Sciences of the United States of America
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2019English

Identifying Ligand-Specific Signalling Within Biased Responses: Focus on Δ Opioid Receptor Ligands

British Journal of Pharmacology
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2014English

Ligand-Based Discovery of a New Scaffold for Allosteric Modulation of the Μ-Opioid Receptor

Journal of Chemical Information and Modeling
Computer Science ApplicationsChemistryChemical EngineeringLibraryInformation Sciences
2015English

Biased Agonism in Drug Discovery - Is It Too Soon to Choose a Path?

Molecular Pharmacology
Molecular MedicinePharmacology
2018English

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