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Publications by Michael S. Wolfe

Γ-Secretase Inhibitors and Modulators for Alzheimer’s Disease

Journal of Neurochemistry
BiochemistryMolecular NeuroscienceCellular
2011English

Γ-Secretase Substrate Selectivity Can Be Modulated Directly via Interaction With a Nucleotide-Binding Site

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2005English

Tumor Necrosis Factor-Α, Interleukin-1β, and Interferon-Γ Stimulate Γ-Secretase-Mediated Cleavage of Amyloid Precursor Protein Through a JNK-dependent MAPK Pathway

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2004English

Direct and Potent Regulation of Γ-Secretase by Its Lipid Microenvironment

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2008English

The Transmembrane Aspartates in Presenilin 1 and 2 Are Obligatory for Γ-Secretase Activity and Amyloid Β-Protein Generation

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2000English

G-Secretase/Presenilin Inhibitors for Alzheimer's Disease Phenocopy Notch Mutations in Drosophila

FASEB Journal
BiochemistryBiotechnologyGeneticsMolecular BiologyMedicine
2002English

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