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Publications by Mike Tyers
An Allosteric Inhibitor of the Human Cdc34 Ubiquitin-Conjugating Enzyme
Cell
Biochemistry
Genetics
Molecular Biology
An Allosteric Conduit Facilitates Dynamic Multisite Substrate Recognition by the SCFCdc4 Ubiquitin Ligase
Nature Communications
Astronomy
Genetics
Molecular Biology
Biochemistry
Chemistry
Physics
Inhibition of SCF Ubiquitin Ligases by Engineered Ubiquitin Variants That Target the Cul1 Binding Site on the Skp1–F-Box Interface
Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
Discovery of Ibomycin, a Complex Macrolactone That Exerts Antifungal Activity by Impeding Endocytic Trafficking and Membrane Function
Cell Chemical Biology
Molecular Medicine
Molecular Biology
Pharmacology
Biochemistry
Clinical Biochemistry
Drug Discovery
Structure/Function Implications in a Dynamic Complex of the Intrinsically Disordered Sic1 With the Cdc4 Subunit of an SCF Ubiquitin Ligase
Structure
Structural Biology
Molecular Biology
Targeting the INCENP IN-box-Aurora B Interaction to Inhibit CPC Activity in Vivo
Open Biology
Biochemistry
Immunology
Genetics
Molecular Biology
Neuroscience
Machine Learning of Global Phosphoproteomic Profiles Enables Discrimination of Direct Versus Indirect Kinase Substrates
Molecular and Cellular Proteomics
Biochemistry
Medicine
Analytical Chemistry
Molecular Biology
Quantification of G1-Cyclin Dynamics in Yeast by Scanning Number and Brightness
Biophysical Journal
Biophysics
Quantification of Nutrient Dependence of SBF/MBF Transcription Factors Controlling Start in Budding Yeast
Biophysical Journal
Biophysics
The Size of the Nucleus Increases as Yeast Cells Grow
Molecular Biology of the Cell
Cell Biology
Molecular Biology