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Publications by P E Czabotar

Crystal Structure of ABT-737 Complexed With BCL-xL: Implications for Selectivity of Antagonists of the BCL-2 Family

Cell Death and Differentiation
Cell BiologyMolecular Biology
2007English

Related publications

ABT-737, a Small Molecule BCL-2/BCL-xL Antagonist, Increases Antimitotic-Mediated Apoptosis in Human Prostate Cancer Cells

PeerJ
GeneticsMolecular BiologyBiochemistryBiological SciencesMedicineAgriculturalNeuroscience
2013English

Synergistic BCL-2 Inhibition by ABT-737 and Cyclosporine A

Apoptosis : an international journal on programmed cell death
Cell BiologyPharmacologyBiochemistryClinical BiochemistryCancer ResearchPharmaceutical Science
2012English

BCL-xL-Inhibitory BH3 Mimetics (ABT-737 or ABT-263) and the Modulation of Cytosolic Calcium Flux and Platelet Function

Blood
BiochemistryImmunologyCell BiologyHematology
2012English

Structure-Based Discovery of a New Class of BCL-xL Antagonists

Bioorganic Chemistry
Organic ChemistryBiochemistryDrug DiscoveryMolecular Biology
2007English

Structure-Based Design of Potent BCL-2/BCL-xL Inhibitors With Strong in Vivo Antitumor Activity

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2012English

The BCL-2 Family Protein Inhibitor, ABT-737, Has Substantial Antimyeloma Activity and Shows Synergistic Effect With Dexamethasone and Melphalan

Clinical Cancer Research
Cancer ResearchOncology
2007English

Synthesis and Evaluation of Apogossypol Atropisomers as Potential BCL-xL Antagonists

Cancer Letters
Cancer ResearchOncology
2009English

The Secrets of the BCL-2 Family

Cell Death and Differentiation
Cell BiologyMolecular Biology
2012English

BCL-2 Antagonists: A Proof of Concept for CLL Therapy

Investigational New Drugs
OncologyPharmacology
2013English

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