Discover open access scientific publications

Search, annotate, share and cite publications

Publications by P. S. George-Hyslop

Proteolytic Processing of the Alzheimer Disease-Associated Presenilin-1 Generates an in Vivo Substrate for Protein Kinase C

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English

Related publications

Homozygosity of the Autosomal Dominant Alzheimer Disease Presenilin 1 E280A Mutation

English

Alzheimer Disease: Presenilin Springs a Leak

Nature Medicine

Molecular Biology

English

Variant Alzheimer Disease With Spastic Paraparesis: A Rare Presenilin-1 Mutation

Canadian Journal of Neurological Sciences

English

Cell Surface Expression of the Alzheimer Disease-Related Presenilin Proteins

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English

Taking Advantage of Physiological Proteolytic Processing of the Prion Protein for a Therapeutic Perspective in Prion and Alzheimer Diseases

Molecular Neuroscience

Infectious Diseases

English

Phenotypic Variability in Autosomal Dominant Familial Alzheimer Disease Due to the S170F Mutation of Presenilin-1

Neurodegenerative Diseases

English

Regulation of Protein Phosphatase 1Iby Cdc25C-Associated Kinase 1 (C-Tak1) and PFTAIRE Protein Kinase

Journal of Biological Chemistry

Molecular Biology

English

Presenilin-1 280Glu→Ala Mutation Alters C-Terminal APP Processing Yielding Longer Aβ Peptides: Implications for Alzheimer’s Disease

Molecular Medicine

Molecular Medicine

Molecular Biology

English

The Proteolytic Fragments of the Alzheimer’s Disease-Associated Presenilin-1 Form Heterodimers and Occur as a 100–150-kDa Molecular Mass Complex

Journal of Biological Chemistry

Molecular Biology

English