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Publications by Rebecca Rawlinson

mTORC1 and DNA-PKcs as Novel Molecular Determinants of Sensitivity to Chk1 Inhibition

Molecular Oncology

Cancer Research

Molecular Medicine

English

γH2AX and Chk1 Phosphorylation as Predictive Pharmacodynamic Biomarkers of Chk1 Inhibitor-Chemotherapy Combination Treatments

Cancer Research

English

Related publications

mTORC1/2 and Protein Translation Regulate Levels of CHK1 and the Sensitivity to CHK1 Inhibitors in Ewing Sarcoma Cells

Molecular Cancer Therapeutics

Cancer Research

English

Targeting Dna Double Strand Break Repair With Hyperthermia and Dna-PKCS Inhibition to Enhance the Effect of Radiation Treatment

English

DNA-PKcs Inhibition Sensitizes Cancer Cells to Carbon-Ion Irradiation via Telomere Capping Disruption

Multidisciplinary

English

Molecular Determinants of Site-Specific Inhibition of Human DNA Topoisomerase I by Fagaronine and Ethoxidine

Journal of Biological Chemistry

Molecular Biology

English

DNA-PKcs, Allostery, and DNA Double-Strand Break Repair

DNA Repair Enzymes: Structure, Biophysics, and Mechanism

English

Tumour Growth Environment Modulates Chk1 Signalling Pathways and Chk1 Inhibitor Sensitivity

Scientific Reports

Multidisciplinary

English

Severe Combined Immunodeficiency Due to DNA-PKcs Deficiency

English

mTORC1 Inhibition Is Required for Sensitivity to PI3K P110 Inhibitors in PIK3CA-Mutant Breast Cancer

Science Translational Medicine

English

Inhibition of Snail1-Dna-PKcs Protein-Protein Interface Sensitizes Cancer Cells and Inhibits Tumor Metastasis

Journal of Biological Chemistry

Molecular Biology

English