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Publications by Sachdev S. Sidhu
Structure-Guided Design Fine-Tunes Pharmacokinetics, Tolerability, and Antitumor Profile of Multispecific Frizzled Antibodies
Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
Saturation Scanning of Ubiquitin Variants Reveals a Common Hot Spot for Binding to USP2 and USP21
Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
Inhibition of SCF Ubiquitin Ligases by Engineered Ubiquitin Variants That Target the Cul1 Binding Site on the Skp1–F-Box Interface
Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15
Structure
Structural Biology
Molecular Biology
Identification and Characterization of Mutations in Ubiquitin Required for Non-Covalent Dimer Formation
Structure
Structural Biology
Molecular Biology
Blockade of TGF-β Signaling With Novel Synthetic Antibodies Limits Immune Exclusion and Improves Chemotherapy Response in Metastatic Ovarian Cancer Models
OncoImmunology
Oncology
Allergy
Immunology
Structural and Functional Characterization of a Ubiquitin Variant Engineered for Tight and Specific Binding to an Alpha-Helical Ubiquitin Interacting Motif
Protein Science
Biochemistry
Medicine
Molecular Biology
Engineered SH2 Domains With Tailored Specificities and Enhanced Affinities for Phosphoproteome Analysis
Protein Science
Biochemistry
Medicine
Molecular Biology
Functional Genomic Characterization of a Synthetic Anti-Her3 Antibody Reveals a Role for Ubiquitination by RNF41 in the Anti-Proliferative Response
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
A Rapid in Vitro Methodology for Simultaneous Target Discovery and Antibody Generation Against Functional Cell Subpopulations
Scientific Reports
Multidisciplinary
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