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Publications by Saima Ghafoor Anjum

HIV-1 Protease Inhibitors From Inverse Design in the Substrate Envelope Exhibit Subnanomolar Binding to Drug-Resistant Variants

Journal of the American Chemical Society

Surface Chemistry

English

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Harnessing Nature’s Insight: Design of Aspartyl Protease Inhibitors From Treatment of Drug-Resistant HIV to Alzheimer’s Disease†

Journal of Medicinal Chemistry

Molecular Medicine

English

Structure-Based Design of Novel HIV-1 Protease Inhibitors to Combat Drug Resistance

English

Lack of Synergy for Inhibitors Targeting a Multi-Drug Resistant Hiv-1 Protease

English

187 Drug Resistance: Crystallography of Drug-Resistant HIV-1 Protease Mutant

Journal of Biomolecular Structure and Dynamics

Molecular Biology

Structural Biology

English

Design, Synthesis, and Biological and Structural Evaluations of Novel HIV-1 Protease Inhibitors to Combat Drug Resistance

Journal of Medicinal Chemistry

Molecular Medicine

English

Toward the Design of Mutation-Resistant Enzyme Inhibitors: Further Evaluation of the Substrate Envelope Hypothesis

Chemical Biology and Drug Design

Organic Chemistry

Molecular Medicine

English

HIV1 Protease Inhibitors Incorporating Stereochemically Defined P2 Ligands to Optimize Hydrogen Bonding in the Substrate Envelope

English

Transition States of Native and Drug-Resistant HIV-1 Protease Are the Same

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

English

Synthesis of Betulinic Acid Derivatives as Entry Inhibitors Against HIV-1 and Bevirimat-Resistant HIV-1 Variants

Bioorganic and Medicinal Chemistry Letters

Organic Chemistry

Molecular Medicine

Molecular Biology

Clinical Biochemistry

Pharmaceutical Science

English