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Publications by Samanthi Perera

A Brain Penetrant Mutant IDH1 Inhibitor Provides in Vivo Survival Benefit

Scientific Reports
Multidisciplinary
2017English

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A Brain-Penetrant MET Inhibitor Achieves Responses in Glioblastoma

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2018English

The Brain-Penetrant Clinical ATM Inhibitor AZD1390 Radiosensitizes and Improves Survival of Preclinical Brain Tumor Models

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Combination Treatment of an IDH1 Inhibitor With Chemotherapy in IDH1 Mutant Acute Myeloid Leukemia

Annals of Hematology
MedicineHematology
2020English

Allosteric Mutant IDH1 Inhibitors Reveal Mechanisms for IDH1 Mutant and Isoform Selectivity

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2017English

Structure Based Discovery of Clomifene as a Potent Inhibitor of Cancer-Associated Mutant IDH1

Oncotarget
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2017English

Mutant IDH1 Disrupts the Mouse Subventricular Zone and Alters Brain Tumor Progression

Molecular Cancer Research
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Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate

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Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR

English

Mutant IDH1 and Seizures in Patients With Glioma

Neurology
Neurology
2017English

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