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Publications by Shivang Vachharajani

Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01

Journal of the American Chemical Society

Surface Chemistry

English

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The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface

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Polyglutamine Disruption of the Huntingtin Exon 1 N Terminus Triggers a Complex Aggregation Mechanism

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The Molecular Tweezer CLR01 Inhibits Aberrant Superoxide Dismutase 1 (SOD1) Self-Assembly in Vitro and in the G93a-Sod1 Mouse Model of ALS

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The Presence of Mitochondria Influences Huntingtin Aggregation

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Emerging Β-Sheet Rich Conformations in Supercompact Huntingtin Exon-1 Mutant Structures

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Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species

Scientific Reports

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The Predicted Structure of the Headpiece of the Huntingtin Protein and Its Implications on Huntingtin Aggregation

Journal of Molecular Biology

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Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers in Vitro and in a Yeast Model of Huntington’s Disease

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Noninvasive Measurement of Protein Aggregation by Mutant Huntingtin Fragments or Α-Synuclein in the Lens

Journal of Biological Chemistry

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