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Publications by Tamio Saito

Affinity-Based Screening of MDM2/MDMX–p53 Interaction Inhibitors by Chemical Array: Identification of Novel Peptidic Inhibitors

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2013English

Loss-Of-Function of a Rice Gibberellin Biosynthetic Gene, GA20 Oxidase (GA20ox-2), Led to the Rice ‘Green Revolution’

Breeding Science
Plant ScienceAgronomyCrop ScienceGenetics
2002English

Related publications

Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach

Chemical Biology and Drug Design
BiochemistryOrganic ChemistryDrug DiscoveryMolecular MedicinePharmacology
2014English

Structures of Low Molecular Weight Inhibitors Bound to MDMX and MDM2 Reveal New Approaches for P53-MDMX/Mdm2 Antagonist Drug Discovery

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
2010English

Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2–p53 Interaction

ACS Medicinal Chemistry Letters
Organic ChemistryBiochemistryDrug Discovery
2014English

Reactivation of P53 by Novel MDM2 Inhibitors: Implications for Pancreatic Cancer Therapy

Current Cancer Drug Targets
Cancer ResearchDrug DiscoveryOncologyPharmacology
2010English

Synthesis of Cell-Permeable Stapled Peptide Dual Inhibitors of the P53-Mdm2/MDMX Interactions via Photoinduced Cycloaddition

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2011English

Discovery of Mdm2-MdmX E3 Ligase Inhibitors Using a Cell-Based Ubiquitination Assay

Cancer Discovery
Oncology
2011English

Image-Based Screening for the Identification of Novel Proteasome Inhibitors

Journal of Biomolecular Screening
Molecular MedicinePharmacologyBiochemistryAnalytical ChemistryBiotechnologyDrug Discovery
2007English

MdmX Protects P53 From Mdm2-Mediated Degradation

Molecular and Cellular Biology
Cell BiologyMolecular Biology
2000English

Identification of Novel Acetylcholinesterase Inhibitors Designed by Pharmacophore-Based Virtual Screening, Molecular Docking and Bioassay

Scientific Reports
Multidisciplinary
2018English

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