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Publications by Trevor M. Penning

Conversion of Human Steroid 5β-Reductase (AKR1D1) Into 3β-Hydroxysteroid Dehydrogenase by Single Point Mutation E120H

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2012English

Mechanisms of Activation of the Transcription Factor Nrf2 by Redox Stressors, Nutrient Cues, and Energy Status and the Pathways Through Which It Attenuates Degenerative Disease

Free Radical Biology and Medicine
BiochemistryPhysiology
2015English

Overexpression of Aldo-Keto Reductase 1C3 (AKR1C3) in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride

Journal of Steroid Biochemistry and Molecular Biology
Molecular MedicineCell BiologyMolecular BiologyBiochemistryEndocrinologyClinical BiochemistryMetabolismDiabetes
2012English

Aldo-Keto Reductase 1C3 Expression in McF-7 Cells Reveals Roles in Steroid Hormone and Prostaglandin Metabolism That May Explain Its Over-Expression in Breast Cancer

Journal of Steroid Biochemistry and Molecular Biology
Molecular MedicineCell BiologyMolecular BiologyBiochemistryEndocrinologyClinical BiochemistryMetabolismDiabetes
2010English

P53Mutagenesis by Benzo[a]pyrene Derived Radical Cations

Chemical Research in Toxicology
MedicineToxicology
2012English

Quantitation of Benzo[a]pyrene Metabolic Profiles in Human Bronchoalveolar (H358) Cells by Stable Isotope Dilution Liquid Chromatography–Atmospheric Pressure Chemical Ionization Mass Spectrometry

Chemical Research in Toxicology
MedicineToxicology
2011English

N-Benzoyl Anthranilic Acid Derivatives as Selective Inhibitors of Aldo–keto Reductase AKR1C3

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2012English

Synthesis of 13c4-Labelled Oxidized Metabolites of the Carcinogenic Polycyclic Aromatic Hydrocarbon Benzo[a]pyrene

Tetrahedron
Organic ChemistryBiochemistryDrug Discovery
2012English

5β-Reduced Steroids and Human Δ4-3-Ketosteroid 5β-Reductase (AKR1D1)

Steroids
Organic ChemistryMolecular BiologyPharmacologyBiochemistryEndocrinologyClinical Biochemistry
2014English

Role of Aldo–keto Reductase Family 1 (AKR1) Enzymes in Human Steroid Metabolism

Steroids
Organic ChemistryMolecular BiologyPharmacologyBiochemistryEndocrinologyClinical Biochemistry
2014English

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