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Publications by Ya-Qiu Long

Incorporation of Piperazino Functionality Into 1,3-Disubstituted Urea as the Tertiary Pharmacophore Affording Potent Inhibitors of Soluble Epoxide Hydrolase With Improved Pharmacokinetic Properties

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2010English

Related publications

1,3-Disubstituted Ureas Functionalized With Ether Groups Are Potent Inhibitors of the Soluble Epoxide Hydrolase With Improved Pharmacokinetic Properties

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2007English

Pharmacokinetic Screening of Soluble Epoxide Hydrolase Inhibitors in Dogs

European Journal of Pharmaceutical Sciences
Pharmaceutical Science
2010English

Substituted Phenyl Groups Improve the Pharmacokinetic Profile and Anti-Inflammatory Effect of Urea-Based Soluble Epoxide Hydrolase Inhibitors in Murine Models

European Journal of Pharmaceutical Sciences
Pharmaceutical Science
2013English

Synthesis and Structure–activity Relationship of Piperidine-Derived Non-Urea Soluble Epoxide Hydrolase Inhibitors

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2013English

Synthesis and SAR of Conformationally Restricted Inhibitors of Soluble Epoxide Hydrolase

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2006English

Solid-Phase Combinatorial Approach for the Optimization of Soluble Epoxide Hydrolase Inhibitors

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2006English

Soluble Epoxide Hydrolase Inhibitors Reduce the Development of Atherosclerosis in Apolipoprotein E-Knockout Mouse Model

Journal of Cardiovascular Pharmacology
Cardiovascular MedicinePharmacologyCardiology
2008English

Discovery of the First Dual Inhibitor of the 5-Lipoxygenase-Activating Protein and Soluble Epoxide Hydrolase Using Pharmacophore-Based Virtual Screening

Scientific Reports
Multidisciplinary
2017English

Mammalian Soluble Epoxide Hydrolase Is Identical to Liver Hepoxilin Hydrolase

Journal of Lipid Research
BiochemistryEndocrinologyCell Biology
2011English

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