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Publications by Yingqian Zhan

Absolute Binding Affinity Calculation for MDM2 Bound to a Disordered Fragment of P53

Biophysical Journal
Biophysics
2013English

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Structures of Low Molecular Weight Inhibitors Bound to MDMX and MDM2 Reveal New Approaches for P53-MDMX/Mdm2 Antagonist Drug Discovery

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
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A Genetic Approach to Mapping the P53 Binding Site in the MDM2 Protein

Molecular Medicine
Molecular MedicineGeneticsMolecular Biology
1997English

Modulation of P53 Binding to MDM2: Computational Studies Reveal Important Roles of Tyr100

BMC Bioinformatics
BiochemistryApplied MathematicsComputer Science ApplicationsStructural BiologyMolecular Biology
2009English

How Does the Recently Discovered Peptide MIP Exhibit Much Higher Binding Affinity Than an Anticancer Protein P53 for an Oncoprotein MDM2?

English

A Water-Swap Reaction Coordinate for the Calculation of Absolute Protein–ligand Binding Free Energies

Journal of Chemical Physics
MedicineTheoretical ChemistryAstronomyPhysicsPhysical
2011English

P53 Mediated Death of Cells Overexpressing MDM2 by an Inhibitor of MDM2 Interaction With P53

Oncogene
Cancer ResearchGeneticsMolecular Biology
1999English

Structure of a Stapled Peptide Antagonist Bound to Nutlin-Resistant Mdm2

PLoS ONE
Multidisciplinary
2014English

Evolution of the P53-Mdm2 Pathway

BMC Evolutionary Biology
EvolutionEcologySystematicsBehavior
2017English

HDMX Stabilizes Mdm2 and P53

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2000English

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