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Publications in Drug Discovery

Arabinosylation Modulates the Growth-Regulating Activity of the Peptide Hormone CLE40a From Soybean

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2017English

Two Are Better Than One: Dual Targeting of Riboswitches by Metabolite Analogs

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2017English

Vitamin D Metabolite, 25-Hydroxyvitamin D, Regulates Lipid Metabolism by Inducing Degradation of SREBP/SCAP

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2017English

Accurate Prediction of Ligand Affinities for a Proton-Dependent Oligopeptide Transporter

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2016English

Blends of Non-Caloric Sweeteners Saccharin and Cyclamate Show Reduced Off-Taste Due to TAS2R Bitter Receptor Inhibition

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2017English

Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2018English

Approaches and Guidelines for the Identification of Novel Substrates of Protein Lysine Methyltransferases

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2016English

Small-Molecule Inhibition of the UNC-Src Interaction Impairs Dynamic SRC Localization in Cells

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2019English

Proteome-Wide Profiling of Clinical PARP Inhibitors Reveals Compound-Specific Secondary Targets

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2016English

At Long Last Potent and Selective KDM5 Inhibitors

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2016English

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