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Publications in Pharmaceutical Science

New Β-Phospholactam as a Carbapenem Transition State Analog: Synthesis of a Broad-Spectrum Inhibitor of Metallo-Β-Lactamases

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2013English

Efficient One-Pot Cyclization/Folding of Rhesus Θ-Defensin-1 (RTD-1)

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2012English

Design, Synthesis and Prostate Cancer Cell-Based Studies of Analogs of the Rho/Mkl1 Transcriptional Pathway Inhibitor, CCG-1423

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

Escape From Adamantane: Scaffold Optimization of Novel P2X7 Antagonists Featuring Complex Polycycles

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2017English

Synthesis and SAR Studies of 5-(Pyridin-4-Yl)-1,3,4-Thiadiazol-2-Amine Derivatives as Potent Inhibitors of Bloom Helicase

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2013English

Microwave Assisted Synthesis and in Vitro Cytotoxicities of Substituted (Z)-2-Amino-5-(1-Benzyl-1h-Indol-3-Yl)methylene-1-Methyl-1h-Imidazol-4(5h)-Ones Against Human Tumor Cell Lines

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

Receptor Activity and Conformational Analysis of 5′-Halogenated Resiniferatoxin Analogs as TRPV1 Ligands

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2011English

Exploration of GGTase-I Substrate Requirements. Part 1: Synthesis and Biochemical Evaluation of Novel Aryl-Modified Geranylgeranyl Diphosphate Analogs

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2016English

Synthesis and Evaluation of Ether-Linked Demethylepipodophyllotoxin Dimers

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2014English

Synthesis and Evaluation of a Series of C5′-Substituted Duocarmycin SA Analogs

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

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