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Ensemble Generation and the Influence of Protein Flexibility on Geometric Tunnel Prediction in Cytochrome P450 Enzymes
PLoS ONE
Multidisciplinary
Distinctive Structural Motifs Coordinate the Catalytic Nucleophile and the Residues of the Oxyanion Hole in the Alpha/Beta-Hydrolase Fold Enzymes
Protein Science
Biochemistry
Medicine
Molecular Biology
JAK Inhibition by Methotrexate (And csDMARDs) May Explain Clinical Efficacy as Monotherapy and Combination Therapy
Journal of Leukocyte Biology
Allergy
Immunology
Cell Biology
Activation of Phospholipase C Β by Gβγ and Gαq Involves C-Terminal Rearrangement to Release Auto-Inhibition
Evaluation of Apoptosis Induction by Concomitant Inhibition of MEK, mTOR, and BCL-2 in Human Acute Myelogenous Leukemia Cells
Molecular Cancer Therapeutics
Cancer Research
Oncology
Inhibition of Flt3 and Pim Kinases by Ec-70124 Exerts Potent Activity in Preclinical Models of Acute Myeloid Leukemia
Molecular Cancer Therapeutics
Cancer Research
Oncology
APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity
Cancer Discovery
Oncology
Inhibition of Gluconeogenic Genes by Calcium-Regulated Heat-Stable Protein 1 via Repression of Peroxisome Proliferator-Activated Receptor Α
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
A Pro-Apoptotic Function of iASPP by Stabilizing P300 and CBP Through Inhibition of BRMS1 E3 Ubiquitin Ligase Activity
Cell Death and Disease
Molecular Neuroscience
Immunology
Cell Biology
Cancer Research
Cellular
Medicine
Inhibition of Endocronartium Harknesii Spore Germination by Metabolites of Scytalidium Uredinicola and S. Album, and the Influence of Growth Medium on Inhibitor Production
Canadian Journal of Botany
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