An Investigation Into the Anti-Hiv Activity of 2′,3′-Didehydro-2′,3′-Dideoxyuridine (D4U) and 2′,3′-Dideoxyuridine (ddU) Phosphoramidate ‘ProTide’ Derivatives

Organic and Biomolecular Chemistry- United Kingdom

doi 10.1039/b904276h

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Date

January 1, 2009

Authors

Youcef Mehellou

Jan Balzarini

Christopher McGuigan

Publisher

Royal Society of Chemistry (RSC)

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An Investigation Into the Anti-Hiv Activity of 2′,3′-Didehydro-2′,3′-Dideoxyuridine (D4U) and 2′,3′-Dideoxyuridine (ddU) Phosphoramidate ‘ProTide’ Derivatives

Organic and Biomolecular Chemistry- United Kingdom

Full Text

Abstract

Categories

Date

Authors

Publisher

Related search

Synthesis of 2', 3'-Didehydro-2', 3'-Dideoxyuridine With Following Addition of Triphenylphosphonium Iodides

D- And L-2, 3-Didehydro-2, 3-Dideoxy-3-Fluoro-Carbocyclic Nucleosides: Synthesis, Anti-Hiv Activity, and Mechanism of Resistance

Pharmacokinetics of the Antiviral Agent -L-3'-Fluoro-2',3'-Didehydro-2',3'-Dideoxycytidine in Rhesus Monkeys

Phosphorylation of 3'-Azido-2',3'-Dideoxyuridine and Preferential Inhibition of Human and Simian Immunodeficiency Virus Reverse Transcriptases by Its 5'-Triphosphate.

Intracellular Metabolism and Persistence of the Anti-Human Immunodeficiency Virus Activity of 2',3'-Didehydro-3'-Deoxy-4'-Ethynylthymidine, a Novel Thymidine Analog

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