P53 Regulation: Teamwork Between RING Domains of Mdm2 and MdmX

Cell Cycle - United States
doi 10.4161/cc.10.24.18662
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Informa UK Limited

Related search

MdmX Protects P53 From Mdm2-Mediated Degradation

Molecular and Cellular Biology
Cell BiologyMolecular Biology
2000English

Targeting P53-Mdm2-MDMX Loop for Cancer Therapy

Sub-Cellular Biochemistry
BiochemistryCancer ResearchCell BiologyMolecular Biology
2014English

Stochastic Modeling and Simulation of the P53-Mdm2/MDMX Loop

Journal of Computational Biology
GeneticsMolecular BiologyComputational TheorySimulationComputational MathematicsMathematicsModeling
2009English

Structures of Low Molecular Weight Inhibitors Bound to MDMX and MDM2 Reveal New Approaches for P53-MDMX/Mdm2 Antagonist Drug Discovery

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
2010English

A Dimethylbromobenzene-Cysteine Stapled Peptide Dual Inhibitor of the P53-Mdm2/MDMX Interactions

Hepatoma Research
2019English

P53 Inactivation by MDM2 and MDMX Negative Feedback Loops in Testicular Germ Cell Tumors

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
2010English

Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach

Chemical Biology and Drug Design
BiochemistryOrganic ChemistryDrug DiscoveryMolecular MedicinePharmacology
2014English

Insight Into the Binding Mechanism of P53/pDIQ-MDMX/Mdm2 With the Interaction Entropy Method

Frontiers in Chemistry
Chemistry
2019English

A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize

Frontiers in Physiology
Physiology
2019English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy