A Novel Synthetic Approach to Very Late Antigen-4 Antagonist Trans-4-[1-[[2,5-Dichloro-4-(1-Methyl-3-Indolylcarboxyamide)phenyl]acetyl]-(4s)-Methoxy-(2s)-Pyrrolidinylmethoxy]cyclohexanecarboxylic Acid via Tert-Butyl Trans-[(4s)-Methoxy-(2s)-Pyrrolidinylmethoxy]cyclohexanecarboxylate as a Key Intermediate
Chemical and Pharmaceutical Bulletin - Japan
doi 10.1248/cpb.59.574
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Date
January 1, 2011
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Pharmaceutical Society of Japan