A Dipolar Cycloaddition Reaction to Access 6-Methyl-4,5,6,7-Tetrahydro-1h-[1,2,3]triazolo[4,5-C]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Antagonist Clinical Candidate

doi 10.1021/acs.jmedchem.7b01279.s001