DnaK as Antibiotic Target: Hot Spot Residues Analysis for Differential Inhibition of the Bacterial Protein in Comparison With the Human HSP70

PLoS ONE - United States
doi 10.1371/journal.pone.0124563
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Public Library of Science (PLoS)

Related search

Relationship Between Hot Spot Residues and Ligand Binding Hot Spots in Protein–Protein Interfaces

Journal of Chemical Information and Modeling
Computer Science ApplicationsChemistryChemical EngineeringLibraryInformation Sciences
2012English

Predicting and Experimentally Validating Hot-Spot Residues at Protein-Protein Interfaces

2019English

Hot-Spot Analysis for Drug Discovery Targeting Protein-Protein Interactions

Expert Opinion on Drug Discovery
Drug Discovery
2018English

The Bacterial Mecanosensitive Channel MscL as a Novel Antibiotic Target

Biophysical Journal
Biophysics
2019English

Characterization of Human Variants in Obesity-Related SIM1 Protein Identifies a Hot-Spot for Dimerization With the Partner Protein ARNT2

Biochemical Journal
BiochemistryCell BiologyMolecular Biology
2014English

Phylogenetic Analysis of Mycoplasmas Based on Hsp70 Sequences: Cloning of the dnaK (Hsp70) Gene Region of Mycoplasma Capricolum

International Journal of Systematic Bacteriology
1997English

The Application of HSP70 as a Target for Gene Therapy

Frontiers in Bioscience - Landmark
ImmunologyMolecular BiologyBiochemistryMicrobiology MedicineGenetics
2006English

Structural Basis for the Inhibition of HSP70 and DnaK Chaperones by Small-Molecule Targeting of a C-Terminal Allosteric Pocket

ACS Chemical Biology
BiochemistryMedicineMolecular Medicine
2014English

Prediction of Hot Spot Residues at Protein-Protein Interfaces by Combining Machine Learning and Energy-Based Methods

BMC Bioinformatics
BiochemistryApplied MathematicsComputer Science ApplicationsStructural BiologyMolecular Biology
2009English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy