Discovery of GNF-5837, a Selective TRK Inhibitor With Efficacy in Rodent Cancer Tumor Models

ACS Medicinal Chemistry Letters - United States
doi 10.1021/ml200261d
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Chemical Society (ACS)

Related search

Selective TRK Inhibitor CH7057288 Against TRK Fusion-Driven Cancer

Molecular Cancer Therapeutics
Cancer ResearchOncology
2018English

The Discovery of a Potent, Selective, and Peripherally Restricted Pan-TRK Inhibitor (PF-06273340) for the Treatment of Pain

English

Structure-Guided Discovery of a Selective McL1 Inhibitor With Cellular Activity

English

A Selective FLT3 Inhibitor Shows Clinical Efficacy in AML

Cancer Discovery
Oncology
2013English

M867, a Novel Selective Inhibitor of Caspase-3 Enhances Cell Death and Extends Tumor Growth Delay in Irradiated Lung Cancer Models

PLoS ONE
Multidisciplinary
2008English

Discovery of a Selective Inhibitor of Oncogenic B-Raf Kinase With Potent Antimelanoma Activity

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2008English

Rogaratinib: A Potent and Selective Pan-FGFR Inhibitor With Broad Antitumor Activity in FGFR-overexpressing Preclinical Cancer Models

International Journal of Cancer
Cancer ResearchOncology
2019English

Combating Acquired TRK Inhibitor Resistance

Cancer Discovery
Oncology
2019English

Discovery of a Novel Nav1.7 Inhibitor From Cyriopagopus Albostriatus Venom With Potent Analgesic Efficacy

Frontiers in Pharmacology
Pharmacology
2018English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy