Akt/mTOR Counteract the Antitumor Activities of Cixutumumab, an Anti-Insulin-Like Growth Factor I Receptor Monoclonal Antibody

Molecular Cancer Therapeutics - United States
doi 10.1158/1535-7163.mct-11-0235
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Association for Cancer Research (AACR)

Related search

Molecular Predictors of Response to a Humanized Anti-Insulin-Like Growth Factor-I Receptor Monoclonal Antibody in Breast and Colorectal Cancer

Molecular Cancer Therapeutics
Cancer ResearchOncology
2009English

Antiapoptotic Signalling by the Insulin-Like Growth Factor I Receptor, Phosphatidylinositol 3-Kinase, and Akt.

Molecular and Cellular Biology
Cell BiologyMolecular Biology
1997English

RAV12 Accelerates the Desensitization of Akt/PKB Pathway of Insulin-Like Growth Factor I Receptor Signaling in COLO205

Cancer Research
Cancer ResearchOncology
2007English

R1507, an Anti-Insulin-Like Growth Factor-1 Receptor (IGF-1R) Antibody, and EWS/FLI-1 siRNA in Ewing's Sarcoma: Convergence at the IGF/IGFR/Akt Axis

PLoS ONE
Multidisciplinary
2011English

Insulin-Like Growth Factor-I-Induced DNA Synthesis in Insulin-Secreting Cell Line RINm5F Is Associated With Phosphorylation of the Insulin-Like Growth Factor-I Receptor and the Insulin Receptor Substrate-2

Journal of Endocrinology
EndocrinologyMetabolismDiabetes
1998English

Regulation of Survival Signals From the Insulin-Like Growth Factor-I Receptor

Biochemical Society Transactions
Biochemistry
2000English

Insulin-Like Growth Factor 1 Receptor Antibody Induces Rhabdomyosarcoma Cell Death via a Process Involving AKT and BCL-xL

Oncogene
Cancer ResearchGeneticsMolecular Biology
2010English

The Three Dimensional Structure of the Type I Insulin-Like Growth Factor Receptor

Molecular Pathology
2001English

Phase I Study of the Anti Insulin-Like Growth Factor 1 Receptor (IGF-1R) Monoclonal Antibody, AVE1642, as Single Agent and in Combination With Bortezomib in Patients With Relapsed Multiple Myeloma

Leukemia
Cancer ResearchOncologyAnesthesiologyPain MedicineHematology
2011English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy