Activation of AXL as a Preclinical Acquired Resistance Mechanism Against Osimertinib Treatment in EGFR-mutant Non-Small Cell Lung Cancer Cells

Molecular Cancer Research - United States
doi 10.1158/1541-7786.mcr-18-0628
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Association for Cancer Research (AACR)

Related search

Mechanism Research of miR‐34a Regulates Axl in Non‐small‐cell Lung Cancer With Gefitinib‐acquired Resistance

Thoracic Cancer
MedicinePulmonaryRespiratory MedicineOncology
2019English

The miR‑625‑3p/AXL Axis Induces Non‑T790M Acquired Resistance to EGFR‑TKI via Activation of the TGF‑β/Smad Pathway and EMT in EGFR‑mutant Non‑small Cell Lung Cancer

Oncology Reports
MedicineCancer ResearchOncology
2020English

Newly Emergent Acquired EGFR Exon 18 G724S Mutation After Resistance of a T790M Specific EGFR Inhibitor Osimertinib in Non-Small-Cell Lung Cancer: A Case Report

OncoTargets and Therapy
OncologyPharmacology
2018English

Cecal Volvulus as a Rare Complication of Osimertinib Dosed at 160 Mg in Patients With EGFR-Mutant Non-Small Cell Lung Cancer

Frontiers in Oncology
Cancer ResearchOncology
2020English

P3.01-95 EGFR Genotype as a Predictor of Survival in EGFR Mutant Non-Small Cell Lung Cancer

Journal of Thoracic Oncology
MedicineOncologyRespiratory MedicinePulmonary
2018English

Inhibition of Casein Kinase 1 Alpha Prevents Acquired Drug Resistance to Erlotinib in EGFR-Mutant Non-Small Cell Lung Cancer

Cancer Research
Cancer ResearchOncology
2015English

Acquired EGFR C797S Mutation Mediates Resistance to AZD9291 in Non–small Cell Lung Cancer Harboring EGFR T790M

Nature Medicine
BiochemistryMedicineGeneticsMolecular Biology
2015English

Osimertinib (AZD9291) Increases Radio‑sensitivity in EGFR T790M Non‑small Cell Lung Cancer

Oncology Reports
MedicineCancer ResearchOncology
2018English

Overcoming T790M Mutant Small Cell Lung Cancer With the Third-Generation EGFR-TKI Osimertinib

Thoracic Cancer
MedicinePulmonaryRespiratory MedicineOncology
2018English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2025 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy