Amanote Research
Register
Sign In
Tumor Targeting With Novel Pyridyl 6Substituted Pyrrolo[2,3d]Pyrimidine Antifolates via Cellular Uptake by Folate Receptor and the Proton-Coupled Folate Transporter and Inhibition of De Novo Purine Nucleotide Biosynthesis
doi 10.1021/acs.jmedchem.7b01708.s001
Full Text
Open PDF
Abstract
Available in
full text
Date
Unknown
Authors
Unknown
Publisher
American Chemical Society (ACS)
Related search
The Human Proton-Coupled Folate Transporter: Determination of Conformation and Identification of the Folate-Binding Pocket
Biophysical Journal
Biophysics
Receptor-Mediated Folate Accumulation Is Regulated by the Cellular Folate Content.
Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
CSF 5-Methyltetrahydrofolate Serial Monitoring to Guide Treatment of Congenital Folate Malabsorption Due to Proton-Coupled Folate Transporter (PCFT) Deficiency
JIMD Reports
Internal Medicine
Genetics
Molecular Biology
Biochemistry
Endocrinology
Metabolism
Diabetes
Multicomponent Folate-Targeted Magnetoliposomes: Design, Characterization, and Cellular Uptake
Nanomedicine: Nanotechnology, Biology, and Medicine
Materials Science
Molecular Medicine
Nanoscience
Pharmaceutical Science
Medicine
Bioengineering
Nanotechnology
Biomedical Engineering
Identification of the Amino Acid Residue Responsible for the Myricetin Sensitivity of Human Proton-Coupled Folate Transporter
Scientific Reports
Multidisciplinary
Evaluation of the Novel Folate Receptor Ligand [18F]fluoro-Peg-Folate for Macrophage Targeting in a Rat Model of Arthritis
Arthritis Research and Therapy
Rheumatology
Allergy
Immunology
Discovery of 5-Substituted Pyrrolo[2,3-D]pyrimidine Antifolates as Dual-Acting Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase in De Novo Purine Nucleotide Biosynthesis: Implications of Inhibiting 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase to AMPK Activation and Antitumor Activity
Journal of Medicinal Chemistry
Drug Discovery
Molecular Medicine
Enzymatic De Novo Pyrimidine Nucleotide Synthesis
Journal of the American Chemical Society
Biochemistry
Colloid
Catalysis
Chemistry
Surface Chemistry
Theranostic Nanoparticles Loaded With Imaging Probes and Rubrocurcumin for Combined Cancer Therapy by Folate Receptor Targeting
ChemMedChem
Organic Chemistry
Molecular Medicine
Pharmacology
Biochemistry
Toxicology
Drug Discovery
Pharmaceutics
