(PDF) A Novel DCM-Associated Mutation in the N-Helix of

A Novel DCM-Associated Mutation in the N-Helix of Cardiac Troponin C Exhibits Impaired Contractile Kinetics and Reduced Ca 2+ -Sensitivity in Vitro

Biophysical Journal - United States

doi 10.1016/j.bpj.2016.11.3011

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Date

February 1, 2017

Authors

Jamie Johnston

David Gonzalez-Martinez

Publisher

Elsevier BV

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A Novel DCM-Associated Mutation in the N-Helix of Cardiac Troponin C Exhibits Impaired Contractile Kinetics and Reduced Ca 2+ -Sensitivity in Vitro

Biophysical Journal - United States

doi 10.1016/j.bpj.2016.11.3011

Full Text

Abstract

Categories

Date

Authors

Publisher

Related search

Weak Domain Stability and Higher Ca 2+ Binding Affinity Contribute to Allostery Between the D/E Linker and N-Helix of Cardiac Troponin C

Skeletal Troponin C Reduces Contractile Sensitivity to Acidosis in Cardiac Myocytes From Transgenic Mice.

A Novel Mutation in TNNC1-ENCODED Cardiac Troponin C Predisposes to Hypertrophic Cardiomyopathy and Recurrent Episodes of Aborted Sudden Cardiac Death

Structure of the Regulatory N-Domain of Human Cardiac Troponin C in Complex With Human Cardiac Troponin I147–163and Bepridil

A Troponin-T Mutation Initiates Cardiac and Skeletal Myopathy Due to Impaired Inhibition of Contraction in Drosophila Melanogaster

A Dilated Cardiomyopathy Troponin C Mutation Lowers Contractile Force by Reducing Strong Myosin-Actin Binding

Cardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics

The R21C Mutation in Cardiac Troponin I Imposes Differences in Contractile Force Generation Between the Left and Right Ventricles of Knock-In Mice

Cardiac Troponin T3: A Distinguishing Parameter Between Contractile and Conducting Cardiac Fibers in Adult Male Mice