mTOR Inhibitors Rescue Premature Lethality and Attenuate Dysregulation of GABAergic/glutamatergic Transcription in Murine Succinate Semialdehyde Dehydrogenase Deficiency (SSADHD), a Disorder of GABA Metabolism

Journal of Inherited Metabolic Disease - Netherlands
doi 10.1007/s10545-016-9959-4
Full Text
Abstract

Available in full text

Categories
Genetics
Date
Authors
Publisher

Wiley

Related search

Decreased GABA-A Binding on FMZ-PET in Succinic Semialdehyde Dehydrogenase Deficiency

Neurology
Neurology
2009English

Succinic Semialdehyde Dehydrogenase Deficiency: An Update

2020English

Succinate Dehydrogenase Deficiency in a PDGFRA Mutated GIST

BMC Cancer
Cancer ResearchOncologyGenetics
2017English

Archaeal Aldehyde Dehydrogenase ST0064 fromSulfolobus Tokodaii, a Paralog of Non-Phosphorylating Glyceraldehyde-3-Phosphate Dehydrogenase, Is a Succinate Semialdehyde Dehydrogenase

Bioscience, Biotechnology and Biochemistry
Organic ChemistryApplied MicrobiologyMolecular BiologyBiochemistryAnalytical ChemistryMedicineBiotechnology
2013English

Elaboration of a Fragment Library Hit Produces Potent and Selective Aspartate Semialdehyde Dehydrogenase Inhibitors

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2015English

Small Molecule Inhibitors of LcrF, a Yersinia Pseudotuberculosis Transcription Factor, Attenuate Virulence and Limit Infection in a Murine Pneumonia Model

Infection and Immunity
ParasitologyInfectious DiseasesImmunologyMicrobiology
2010English

A Ketogenic Diet Rescues the Murine Succinic Semialdehyde Dehydrogenase Deficient Phenotype

Experimental Neurology
Developmental NeuroscienceNeurology
2008English

Molecular Docking and Enzymatic Evaluation to Identify Selective Inhibitors of Aspartate Semialdehyde Dehydrogenase

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2012English

Mammalian Methylmalonate-Semialdehyde Dehydrogenase

Methods in Enzymology
2000English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy