DNA Aptamers Targeting BACE1 Reduce Amyloid Levels and Rescue Neuronal Deficiency in Cultured Cells

Molecular Therapy - Nucleic Acids - United States
doi 10.1016/j.omtn.2019.02.025
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Elsevier BV

Related search

Impact of RTN3 Deficiency on Expression of BACE1 and Amyloid Deposition

Journal of Neuroscience
Neuroscience
2014English

Deficiency of Neuronal P38α MAPK Attenuates Amyloid Pathology in Alzheimer Disease Mouse and Cell Models Through Facilitating Lysosomal Degradation of BACE1

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2015English

Neuronal Cx3cr1 Deficiency Protects Against Amyloid Β-Induced Neurotoxicity

PLoS ONE
Multidisciplinary
2015English

Genome-Wide Association Study Links APOEϵ4 and BACE1 Variants With Plasma Amyloid Β Levels

2017English

Non-Neuronal Cells Exacerbate -Amyloid Aggregation in the Aged Brain

Journal of Neuroscience
Neuroscience
2014English

Amyloid Β Levels in Human Red Blood Cells

PLoS ONE
Multidisciplinary
2012English

Lysosomal NEU1 Deficiency Affects Amyloid Precursor Protein Levels and Amyloid-Β Secretion via Deregulated Lysosomal Exocytosis

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2013English

Novel Role of RanBP9 in BACE1 Processing of Amyloid Precursor Protein and Amyloid Β Peptide Generation

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2009English

Fluorescence Micro-Spectroscopy Assessment of the in Vitro Dimerization of BACE1-GFP Fusion Protein in Cultured Cells

Biophysical Journal
Biophysics
2016English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy