Discover open access scientific publications

Search, annotate, share and cite publications

Publications by Eric Hales

Discovery of 5-Substituted Pyrrolo[2,3-D]pyrimidine Antifolates as Dual-Acting Inhibitors of Glycinamide Ribonucleotide Formyltransferase and 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase in De Novo Purine Nucleotide Biosynthesis: Implications of Inhibiting 5-Aminoimidazole-4-Carboxamide Ribonucleotide Formyltransferase to AMPK Activation and Antitumor Activity

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2013English

Related publications

5-Aminoimidazole-4-Carboxamide Ribonucleotide-Transformylase and Inosine-Triphosphate-Pyrophosphatase Genes Variants Predict Remission Rate During Methotrexate Therapy in Patients With Juvenile Idiopathic Arthritis

Pediatric Rheumatology
ImmunologyPediatricsRheumatologyAllergyPerinatologyChild Health
2014English

Synthesis and Evaluation of a Classical 2,4-Diamino-5-Substituted-Furo[2,3-D]pyrimidine and a 2-Amino-4-Oxo-6-Substituted-Pyrrolo[2,3-D]pyrimidine as Antifolates

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2006English

Enhancement of Insulin-Mediated Rat Muscle Glucose Uptake and Microvascular Perfusion by 5-Aminoimidazole-4-Carboxamide-1-Β-D-Ribofuranoside

Cardiovascular Diabetology
Internal MedicineCardiologyEndocrinologyCardiovascular MedicineMetabolismDiabetes
2015English

5-Aminoimidazole-4-Carboxamide Ribonucleoside-Mediated Adenosine Monophosphate-Activated Protein Kinase Activation Induces Protective Innate Responses in Bacterial Endophthalmitis

Cellular Microbiology
VirologyImmunologyMicrobiology
2016English

Activation of AMP-Activated Protein Kinase by 5-Aminoimidazole-4-Carboxamide-1- -D-Ribofuranoside in the Muscle Microcirculation Increases Nitric Oxide Synthesis and Microvascular Perfusion

Arteriosclerosis, Thrombosis, and Vascular Biology
Cardiovascular MedicineCardiology
2010English

Asymmetric Synthesis of Inhibitors of Glycinamide Ribonucleotide Transformylase

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2008English

Synthesis of Classical, Four-Carbon Bridged 5-Substituted Furo[2,3-D]pyrimidine and 6-Substituted Pyrrolo[2,3-D]pyrimidine Analogues as Antifolates1

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2005English

The Effect of 5-Aminoimidazole-4-Carboxamide Ribonucleoside (AICAR) on Fatty Acid Oxidation in Hepatocytes Isolated From Neonatal Piglets

Journal of Animal Science and Biotechnology
Animal ScienceZoologyFood ScienceBiochemistryBiotechnology
2012English

5-Aminoimidazole-4-Carboxamide Riboside Induces Apoptosis in Jurkat Cells, but the AMP-activated Protein Kinase Is Not Involved

Biochemical Journal
BiochemistryCell BiologyMolecular Biology
2003English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy