Discover open access scientific publications

Search, annotate, share and cite publications

Publications by Ernest Hamel

Novel 3-Substituted 7-Phenylpyrrolo[3,2-F]quinolin-9(6h)-Ones as Single Entities With Multitarget Antiproliferative Activity

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2015

English

Structure–Activity Relationship and in Vitro and in Vivo Evaluation of the Potent Cytotoxic Anti-Microtubule AgentN-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium Chloride and Its Analogues as Antitumor Agents

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2013

English

Synthesis and Antitumor Activity of 1,5-Disubstituted 1,2,4-Triazoles as Cis-Restricted Combretastatin Analogues

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2010

English

Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives as a Novel Class of Potent Antimitotic Agents

Journal of Medicinal Chemistry

Drug Discovery

Molecular Medicine

2013

English

MG-2477, a New Tubulin Inhibitor, Induces Autophagy Through Inhibition of the Akt/mTOR Pathway and Delayed Apoptosis in A549 Cells

Biochemical Pharmacology

Biochemistry

Pharmacology

2012

English

Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents

Scientific Reports

Multidisciplinary

2017

English

Synthesis and Biological Evaluation of 2-(3′,4′,5′-Trimethoxybenzoyl)-3-Aryl/Arylaminobenzo[b]thiophene Derivatives as a Novel Class of Antiproliferative Agents

European Journal of Medicinal Chemistry

English

Cytotoxic Activities of Substituted 3-(3,4,5-Trimethoxybenzylidene)-1,3-Dihydroindol-2-Ones and Studies on Their Mechanisms of Action

European Journal of Medicinal Chemistry

English

A Screen for Kinetochore-Microtubule Interaction Inhibitors Identifies Novel Antitubulin Compounds

PLoS ONE

Multidisciplinary

2010

English

Synthesis, Anti-Tubulin and Antiproliferative SAR of Steroidomimetic Dihydroisoquinolinones

English

Amanote Research

Discover open access scientific publications

Search, annotate, share and cite publications

Publications by Ernest Hamel

Novel 3-Substituted 7-Phenylpyrrolo[3,2-F]quinolin-9(6h)-Ones as Single Entities With Multitarget Antiproliferative Activity

Structure–Activity Relationship and in Vitro and in Vivo Evaluation of the Potent Cytotoxic Anti-Microtubule AgentN-(4-Methoxyphenyl)-N,2,6-trimethyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-aminium Chloride and Its Analogues as Antitumor Agents

Synthesis and Antitumor Activity of 1,5-Disubstituted 1,2,4-Triazoles as Cis-Restricted Combretastatin Analogues

Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[b]thiophene Derivatives as a Novel Class of Potent Antimitotic Agents

MG-2477, a New Tubulin Inhibitor, Induces Autophagy Through Inhibition of the Akt/mTOR Pathway and Delayed Apoptosis in A549 Cells

Synthesis and Biological Evaluation of 2-Methyl-4,5-Disubstituted Oxazoles as a Novel Class of Highly Potent Antitubulin Agents

Synthesis and Biological Evaluation of 2-(3′,4′,5′-Trimethoxybenzoyl)-3-Aryl/Arylaminobenzo[b]thiophene Derivatives as a Novel Class of Antiproliferative Agents

Cytotoxic Activities of Substituted 3-(3,4,5-Trimethoxybenzylidene)-1,3-Dihydroindol-2-Ones and Studies on Their Mechanisms of Action

A Screen for Kinetochore-Microtubule Interaction Inhibitors Identifies Novel Antitubulin Compounds

Synthesis, Anti-Tubulin and Antiproliferative SAR of Steroidomimetic Dihydroisoquinolinones