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Publications by Graeme Robertson

Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach

Chemical Biology and Drug Design
BiochemistryOrganic ChemistryDrug DiscoveryMolecular MedicinePharmacology
2014English

Related publications

Affinity-Based Screening of MDM2/MDMX–p53 Interaction Inhibitors by Chemical Array: Identification of Novel Peptidic Inhibitors

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2013English

Synthesis of Cell-Permeable Stapled Peptide Dual Inhibitors of the P53-Mdm2/MDMX Interactions via Photoinduced Cycloaddition

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2011English

A Dimethylbromobenzene-Cysteine Stapled Peptide Dual Inhibitor of the P53-Mdm2/MDMX Interactions

Hepatoma Research
2019English

MdmX Protects P53 From Mdm2-Mediated Degradation

Molecular and Cellular Biology
Cell BiologyMolecular Biology
2000English

Targeting P53-Mdm2-MDMX Loop for Cancer Therapy

Sub-Cellular Biochemistry
BiochemistryCancer ResearchCell BiologyMolecular Biology
2014English

Human Epidermal Growth Factor Receptor 4 (Her4) Suppresses P53 Protein via Targeting the MDMX-MDM2 Protein Complex

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2016English

Structures of Low Molecular Weight Inhibitors Bound to MDMX and MDM2 Reveal New Approaches for P53-MDMX/Mdm2 Antagonist Drug Discovery

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
2010English

P53 Regulation: Teamwork Between RING Domains of Mdm2 and MdmX

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
2011English

Stochastic Modeling and Simulation of the P53-Mdm2/MDMX Loop

Journal of Computational Biology
GeneticsMolecular BiologyComputational TheorySimulationComputational MathematicsMathematicsModeling
2009English

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