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Publications by Guy A. Higgins
Chronic Treatment With the Γ-Secretase Inhibitor LY-411,575 Inhibits Β-Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Related publications
Β-Secretase Cleavage at Amino Acid Residue 34 in the Amyloid Β Peptide Is Dependent Upon Γ-Secretase Activity
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Equimolar Production of Amyloid Β-Protein and Amyloid Precursor Protein Intracellular Domain From Β-Carboxyl-Terminal Fragment by Γ-Secretase
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
The Role of Γ-Secretase Activating Protein (GSAP) and Imatinib in the Regulation of Γ-Secretase Activity and Amyloid-Β Generation
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Identification of Two Novel Synaptic Γ-Secretase Associated Proteins That Affect Amyloid Β-Peptide Levels Without Altering Notch Processing
Neurochemistry International
Molecular Neuroscience
Cell Biology
Cellular
The Ubiquitin Ligase Synoviolin Up-Regulates Amyloid Β Production by Targeting a Negative Regulator of Γ-Secretase, Rer1, for Degradation
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
The Low Density Lipoprotein Receptor-Related Protein 1B Retains Β-Amyloid Precursor Protein at the Cell Surface and Reduces Amyloid-Β Peptide Production
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Γ-Secretase Inhibitor Alleviates Acute Airway Inflammation of Allergic Asthma in Mice by Downregulating Th17 Cell Differentiation
Mediators of Inflammation
Immunology
Cell Biology
The Transmembrane Aspartates in Presenilin 1 and 2 Are Obligatory for Γ-Secretase Activity and Amyloid Β-Protein Generation
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Intramembrane Proteolysis of Β-Amyloid Precursor Protein by Γ-Secretase Is an Unusually Slow Process
Biophysical Journal
Biophysics
